| 01/23/10 | Sat | Alumni Game | NAIA | Downs Field | 1:00 PM |
| 01/30/10 | Sat | Wayland Baptist University (DH) | NAIA | Downs Field | 1:00 PM |
| 01/31/10 | Sun | Mount Mercy College (DH) | NAIA | Downs Field | 3:00 PM |
| 02/01/10 | Mon | Mount Mercy College (DH) | NAIA | Downs Field | 1:00 PM |
| 02/05/10 | Fri | Southern Nazarene University (DH) | NAIA | Downs Field | 1:00 PM |
| 02/06/10 | Sat | Southern Nazarane University (DH) | NAIA | Downs Field | 11:00 AM |
| 02/20/10 | Sat | Northwestern State University (DH) | NAIA | Downs Field | 1:00 PM |
| 02/21/10 | Sun | Northwestern State University (DH) | NAIA | Downs Field | 1:00 PM |
| 03/02/10 | Tue | Prarie View University (DH) | NCAA I | Prarie View | 1:00 PM |
| 03/03/10 | Wed | University of Houston- Victoria (DH) | NAIA | Victoria, Texas | 5:00 PM |
| 03/05/10 | Fri | Southwestern Assemblies of God Univ. (DH) | RRAC | Downs Field | 1:00 PM |
| 03/06/10 | Sat | Southwestern Assemblies of God Univ.(S) | RRAC | Downs Field | 1:00 PM |
| 03/12/10 | Fri | Robert Morris Univ. (DH) | NAIA | Downs Field | 1:00 PM |
| 03/13/10 | Sat | Robert Morris Univ. (1) | NAIA | Downs Field | 1:00 PM |
| 03/14/10 | Sun | Nebraska Wesleyan University (DH) | NCAA III | Downs Field | 1:00 PM |
| 03/16/10 | Tue | Concordia Wesleyan Univ (1) | NAIA | Downs Field | 11:00 AM |
| 03/19/10 | Fri | Wiley College (DH) | RRAC | Downs Field | 12:00 PM |
| 03/20/10 | Sat | Wiley College (S) | RRAC | Downs Field | 12:00 PM |
| 03/26/10 | Fri | Jarvis Christian College (DH) | RRAC | Hawkins, Texas | 12:00 PM |
| 03/27/10 | Sat | Jarvis Christian College (S) | RRAC | Hawkins, Texas | 1:00 PM |
| 03/28/10 | Sun | Texas Southern Univ. (DH) | NCAA I | Houston, Texas | 1:00 PM |
| 03/29/10 | Mon | Texas Southen Univ (S) | NCAA I | Houston, Texas | 1:00 PM |
| 03/30/10 | Tue | Concordia University - Austin (DH) | NCAA III | Concordia | 4:00 PM |
| 03/31/10 | Wed | Texas Southern University (S) | NCAA I | Downs Field | 2:00 PM |
| 04/02/10 | Fri | University of Texas - Brownsville (DH) | RRAC | Downs Field | 3:00 PM |
| 04/03/10 | Sat | University Texas-Brownsville (S) | RRAC | Downs Field | 12:00 PM |
| 04/07/10 | Wed | University of Houston-Victoria | RRAC | Downs Field | 2:00 PM |
| 04/16/10 | Fri | Texas College (DH) | RRAC | Tyler, Texas | 12:00 PM |
| 04/17/10 | Sat | Texas College (S) | RRAC | Tyler, Texas | 12:00 PM |
| 04/20/10 | Tue | Howard Payne University (DH) | NCAA III | Brownwood, Texas | 1:00 PM |